Pre-reg Q&As: closed book practice paper
1
Multiple Completion
Directions: For the question below, ONE or MORE of the responses is (are) correct. Decide which of the responses is (are) correct. Then choose:
A if 1,2 and 3 are correct
B if 1 and 2 only are correct
C if 2 and 3 only are correct
D if 1 only is correct
E if 3 only is correct
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Directions Summarised |
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A 1,2,3 |
B 1,2 |
C 2,3 |
D 1 only |
E 3 only |
The Responsible Pharmacist Regulations 2008, which came into force on 1 October 2009, replaced the following provisions in the Medicines Act 1968.
1. Personal control
2. Supervision
3. Superintendent pharmacist
2
Simple Completion
Directions: The question is followed by five suggested answers. Select the best answer.
The supply of which one of the following would be unlawful? Select the best answer.
A. A prescription for six weeks supply of a Schedule 2 Controlled Drug issued three weeks previously (and not forward dated).
B. A prescription for 28 days supply of a Schedule 3 Controlled Drug issued six weeks previously (and not forward dated).
C. A prescription for 28 days supply of a Schedule 2 Controlled Drug issued three weeks previously (and not forward dated), with the total quantity written only in figures.
D. A repeat supply, made six weeks after the original dispensing, of a Schedule 4 Controlled Drug for which repeats are allowed, on a private prescription requesting one repeat but with no specification, either of the date or length of time after the initial supply, as to when the repeat is to be made.
E. A repeat supply, made one year after the original dispensing, of a Schedule 5 Controlled Drug on a private prescription requesting one repeat, but with no specification, either of the date or length of time after the initial supply, as to when the repeat is to be made.
3
In order to make 200ml of Gentian Mixture Alkaline BP, which contains 50 per cent double strength chloroform water, you would need to use:
1. 0.25ml of chloroform
2. 2.5ml of concentrated chloroform water, which contains 10 per cent chloroform
3. 10ml of chloroform spirit, which contains chloroform 1 part in 20
One or more of the responses below is (are) correct. Decide which of the responses is (are) correct. Then choose:
A if 1, 2 and 3 are correct
B if 1 and 2 only are correct
C if 2 and 3 only are correct
D if 1 only is correct
E if 3 only is correct
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Directions Summarised |
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A 1,2,3 |
B 1,2 |
C 2,3 |
D 1 only |
E 3 only |
4
The question consists of four lettered headings followed by a list of numbered questions. For each numbered question select the one heading which is most closely related to it. Each heading may be used once, more than once, or not at all.
Which one of the over-the counter medicines (select from A to D) should not be sold to a patient who is taking one of the prescription medicines below:
A Dulcolax tablets (bisacodyl)
B Imodium capsules (loperamide)
C Nurofen tablets (ibuprofen)
D Sudafed tablets (pseudoephedrine)
1. Lithium carbonate
2. Phenelzine
5
Multiple Completion
Directions: For the question below, ONE or MORE of the responses is (are) correct. Decide which of the responses is (are) correct. Then choose:
For the question below, ONE or MORE of the responses is (are) correct. Decide which of the responses is (are) correct. Then choose:
A if 1,2 and 3 are correct
B if 1 and 2 only are correct
C if 2 and 3 only are correct
D if 1 only is correct
E if 3 only is correct
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Directions Summarised |
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A 1,2,3 |
B 1,2 |
C 2,3 |
D 1 only |
E 3 only |
Which of the following symptoms might indicate that a patient who is taking levothyroxine is on too high a dose?
1. Diarrhoea
2. Sweating
3. Weight gain
6
Simple Completion
Directions: The question is followed by five suggested answers. Select the best answer.
A pregnant woman taking medication for which one of the following conditions is at increased risk of giving birth to a baby with spina bifida?
A. Asthma
B. Crohn's disease
C. Diabetes
D. Epilepsy
E. Hypertension
7
Multiple Completion
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Directions Summarised
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A
1,2,3
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B
1,2
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C
2,3
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D
1 only
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E
3 only
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3. A person who has previously been prescribed the medicine by a dentist in the United Kingdom
Your pharmacy participates in a ‘Heart Health' scheme run by your local PCT, in which you measure patients' height, weight, blood pressure and, depending on results, offer lifestyle advice or refer them to their GP. A 40 year old male patient weighs 70 kg and is 1.8 metres in height. His blood pressure is 160/110mmHg.
Assertion/Reason
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First statement
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Second statement
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He should be referred to his GP.
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He is overweight.
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Directions Summarised
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First statement
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Second statement
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A
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True
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True
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2nd statement is a correct explanation of the first
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B
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True
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True
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2nd statement is not a correct explanation of the first
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C
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True
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False
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D
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False
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True
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E
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False
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False
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9
Simple Completion
10
Directions: There are four headings below, followed by three questions relating to charges for private prescriptions. For each question select the one heading which is the most closely related to it. Each heading may be used once, more than once, or not at all.
A £9.20
B £9.50
C £10.90
D £11.20
For private prescriptions, a community pharmacy charges 25 per cent on the net cost of the item plus a £2 dispensing fee. If the net cost of an item is £6, which one of the above prices should be charged for:
1. A private prescription for a 66 year old man
2. A private prescription for an 8 year old girl
3. A veterinary prescription for a dog
Answers
1: D (1 only)
Rationale/Explanation
The Health Act 2006 replaced the term "personal control" in the Medicines Act 1968 with the concept of a "responsible pharmacist"; the Responsible Pharmacist Regulations 2008 will bring that into effect. These will underpin any changes to supervision, proposals for which are likely to be published later this year, although they would not come into force until at least 2010. There are currently no proposals to amend the superintendent pharmacist provisions.
2:B
Rationale/Explanation
Only B is prohibited by the Misuse of Drugs Regulations: prescribers have been advised by the Department of Health and the Scottish Executive not to prescribe more than 30 days supply of a Controlled Drug in Schedule 2, 3 or 4, but it is not unlawful to do so or for pharmacists to supply more than 30 days if prescribed.
Pharmacists can correct minor technical errors or omissions on CD scripts, and this applies to C. So long as the initial supply of a Schedule 4 CD is made within 28 days of being prescribed, and for a Schedule 5 CD within six months, there is no restriction on when repeats can be supplied. The question is closed book because pharmacists are expected to be conversant with the rules for supply of CDs and not have to look them up.
3: E (3 only)
Rationale/Explanation
Chloroform water contains 1 part chloroform in 400 (0.25 per cent). The question asks for the quantities required to prepare 100ml of double strength chloroform water.
Using the concentrations given in the question, it can be calculated that 0.5ml of chloroform, 5ml of concentrated chloroform water, or 10ml of chloroform spirit would be required to prepare 100ml of double strength chloroform water. Thus, only answer 3 is correct.
Notes
The question requires an understanding of concentration as expressed in percentages and as 'parts in', and the ability to manipulate them. The question is Closed Book because pharmacists and trainees should know the concentration of chloroform in chloroform water without having to look it up.
Rationale/Explanation
Lithium interacts with ibuprofen, an NSAID, reducing lithium excretion and increasing the risk of toxicity.
Phenelzine, a MAOI, interacts with pseudoephedrine, a sympathomimetic decongestant, causing blood pressure to rise with a risk of hypertensive crisis
5: B (1 and 2 only)
Rationale/Explanation
Diarrhoea and sweating are symptoms of a hyperthyroid state; weight gain indicates a hypothyroid state.
6: D
Rationale
There is an increased risk of neural tube defects in babies associated with the use of antiepileptic drugs during pregnancy. Spina bifida is a neural tube defect.
7: A (All three correct)
Rationale
Since November 2008, as result of an EU directive, pharmacists can make emergency supplies of prescription only medicines that have been previously prescribed by a practising doctor or dentist in Switzerland and the European Economic Area, which includes all EU states plus Norway, Iceland and Liechtenstein.
In May 2009, the Medicines Act 1968 regulations were amended to allow emergency supplies of POMs previously prescribed by a UK dentist.
8: C (true/false)
Calculation: 70 / 1.8x1.8 = 70 / 3.24 = 21.6
A BMI between 18.5 and 24.9 is considered normal, so the patient is not overweight. However, he should be referred to his GP because his blood pressure is above the generally accepted target level of 140/90mmHg.
9: D
Rationale
Akathisia (uncontrollable motor restlessness), dystonia (involuntary jerking movements of the trunk and limbs) and tardive dyskinesia (twitching, mainly of the face and tongue) can be experienced by both men and women. Galactorrhoea (spontaneous flow of breast milk) is exclusive to women. Gynaecomastia is excessive breast development in males.
Note
Pharmacists are expected to be familiar with medical terminology.
10: 1 B, 2 B, 3 C
Rationale/calculation
Private prescriptions for humans are zero rated for VAT; veterinary prescriptions are subject to VAT at the standard rate (currently 15 per cent).
Q 1 and 2: Cost of item: £6, plus 25 per cent (£1.50) = £7.50 + £2 = £9.50. (Age and gender of patients are irrelevant).
Q3: As for 1 and 2, plus VAT (£9.50 + 15 per cent [£1.43]) = £10.93 (nearest suggested answer = £10.90).
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