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GPs pressured to prescribe cheaper cholesterol-lowering medicines

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As long as the patients are regularly reviewed and given blood lipid screening while on a statin then there should not be an issue with cost effective prescribing. Given atorvastatin is now generic then prescribing within NICE guidelines should not be a problem, rosuvastatin is now being targeted by medicines management teams. There is a case for this where it has been prescribed first line for primary prevention instead of simva or atorva. Ezetimibe is only resorted to if there is statin intolerance.
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GPs pressured to prescribe cheaper cholesterol-lowering medicines
Answer
02/07/12 17:13as a reply to Gerry Diamond.
Statins are not the same. Many talk about the class effect of statins.

We know atorva has a long half life so can be given mane as opposed to nocte like other statins. If you look at atorva more carefully you will find that it has other benefits apart from reducing reducing TC and increasing HDL it also has adhesion properties that stabilise plaques and prevent atheroma 's from coming away from vessel walls and occluding.

The benefits of atorva gave been seen by interventionist cardiologists that can see the plaque stabilisation with atorva during angiography compared to patients on other statins.

If I needed a statin I would fight tooth and nail for atorva other any other statin. It's other properties really do make it the statin of choice - the government needs to wake up and listen and take note of the evidence. Maybe then healthcare professionals across the board can put their patients first and help deliver a first class world service.
GPs pressured to prescribe cheaper cholesterol-lowering medicines
Answer
02/07/12 18:46as a reply to Gerry Diamond.
Statin switching protocols adhere strictly to NICE guidelines and it is an exageration to say GPs were compelled to switch patients. PCTs switched in primary prevention mostly, hospitals post MI depending on their protocols prescribed simvastatin or atorvastatin 80mg. Ethically it is unjustifiable to use NHS money where equal therapeutic effects can be gained using cost effective prescribing, since atorvastatin is available as a generic then that should not be an issue. I think fighting tooth and nail is unnecessary and if someone has familial hyperlipidaemia then they would be titrated on 1st line, second line and third line statins ensuring the dose was maximised to tolerability before changing, then ezetimibe may be added.
GPs pressured to prescribe cheaper cholesterol-lowering medicines
Answer
04/07/12 18:39as a reply to Gerry Diamond.
Atorvastatin and simvastatin both have patient orientated outcome data from high quality randomised controlled trials, there is very little to choose between them on evidence; if anything simvastatin has more evidence than atorvastatin. Simvastatin remains the least expensive and is therefore the first line statin allowing best use of finite NHS resources. As the price of atorvastatin falls an increase will reasonably be seen.

Rosuvastatin has no good PATIENT orientated outcome data and would thus not be first choice for most people.

It really is that simple, if safety, equivalent dosing ie simvastatin 40mg/atorvastatin 10mg and efficacy are equal as they are for simvastatin and atorvastatin then in a finite funded health economy it is perfectly reasonable to choose the least expensive as the first line option.

A decision to use the most expensive drug will simply mean other patients are possibly denied other treatments due to the lost opportunity cost, there is not a bottomless pit

Besides the survey was commissioned by MSD there may be bias! Has Dr Neely got concrete evidence of patient harm, I note he is quoted as 'could'
GPs pressured to prescribe cheaper cholesterol-lowering medicines
Answer
09/07/12 16:19as a reply to Gerry Diamond.
The whole point of prescribing with an evidence base is to have some rational basis for prescribing. GPs should not be reluctant to give ezetimibe if that is the only option open eg statin intolerance etc.
It is perfectly reasonable to select a lower cost option - if it is clinically appropriate to do so. Continual advances mean the drugs bill will never go down and besides, there would be longer episodes of ill health and hospital stays without them !!
RE: GPs pressured to prescribe cheaper cholesterol-lowering medicines
Answer
10/07/12 15:32as a reply to Gerry Diamond.
Any evidence of what you claiming ?

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