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22 Aug 2012

MHRA announces new contraindications for simvastatin

Clinical Simvastatin is now contraindicated with ciclosporin, danazol and gemfibrozil following evidence of an increased risk of myopathy or rhabdomyolysis...
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Gerry Diamond, Other pharmacist
Posted on 23 August 2012.
Very useful info for all pharmacists esp wrt to MURs.
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Leanne Macdonald, Locum pharmacist
Posted on 30 October 2012.
If patients have been on the combination of simv 40mg and amlodipine for a number of years with no problems, then I can't understand why GPs are being advised to reduce the simv dose or switch to a different statin; since surely it is unlikely they are going to experience problems now?? Am I missing something??
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