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How does pre-exposure prophylaxis reduce the risk of HIV infection?

How does pre-exposure prophylaxis reduce the risk of HIV infection?

Christiana, a 27-year-old transgender woman who has sex with men, recently heard that pre-exposure human immunodeficiency virus (HIV) prophylaxis (PrEP) is going to be available through the NHS England. She has a few questions for you and would like to know how PrEP works and whether it is suitable for her.

What is PrEP?

PrEP is a HIV protection strategy that is used to prevent people who are HIV negative from becoming infected with it. The tablet contains two antiretroviral drugs, emtricitabine 200mg and tenofovir disoproxil 245mg.(1) These drugs are both regularly prescribed for treatment of HIV infection - they are safe to use and serious side effects are rare.(2)

How does PrEP work?

Emtricitabine and tenofovir disoproxil are nucleoside analogues of cytidine and adenosine

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