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Update module 1404: Ulcerative colitis

Update module 1404: Ulcerative colitis

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What is the main role of aminosalicylates in ulcerative colitis (UC)? Why should a patient on azathioprine be advised to report a sore throat? Do you know what the Montreal classification is?


If you feel you need to know more about UC, this article focuses on drug treatment while also considering the signs, symptoms and diagnosis.

Key points

• UC is an uncommon chronic relapsing inflammatory disease involving the rectum and a variable extent of colon.

• Patients with UC present commonly with frequent bloody diarrhoea and low abdominal pain. Infection and Crohn's disease must be considered in the differential diagnosis.

• Initial treatment involves aminosalicylates and/or corticosteroids, administered by mouth or rectum depending on the extent

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