The incorrect information was given for the total sucrose content and daily maximum dose, which was stated on methadone oral solution 1mg/ml and methadone mixture 1mg/ml.

The accurate data of both products is 441.5mg/ml total sucrose content and 26.49g daily maximum dose.

The methadone had incorrectly stated these quantities as 197.17mg/ml and 11.83g respectively.

Martindale said: “We sincerely apologise for any inconvenience caused by this misinformation.”

It had submitted a “variation to amend this error”, in the summary of product characteristics (SmPC) and the patient information leaflet (PIL), to the Medicines & Healthcare Products Regulatory Agency (MHRA), it added.

The current SmPC and PIL for these products “have now been updated with the correct quantity of sucrose”, it said.