Heath Pharmacy was petrol bombed around 2am on Friday (January 3), but the pharmacy was still open throughout the day.
The police were called to the premises by the fire service and the attack was captured on CCTV, which can be viewed below, along with images of the damage caused.
The two suspects exited a car, smashed the window on the front door and threw two milk bottles containing petrol into the pharmacy, Heath Pharmacy manager Amanda Smith told C+D.
“Luckily our floor mat soaked most of [the petrol] up, so it didn’t cause too much damage,” she explained.
Ms Smith said most of the damage was in the store, and there was “smoke damage only” in the dispensary.
The pharmacy team had to “clean everything” on Friday morning, as the branch was “covered in soot”.
“We stayed open throughout, with customers using the side delivery door,” Ms Smith said.
West Yorkshire Police confirmed that no-one was harmed during the attack.
Detectives are appealing for information and anyone who thinks they may have seen something can contact Calderdale CID by calling 101 or using the online 101 chat, quoting crime reference 13200003109.
It is not yet known why the pharmacy was attacked.