Chemist + Druggist is part of Pharma Intelligence UK Limited

This is operated by Pharma Intelligence UK Limited, a company registered in England and Wales with company number 13787459 whose registered office is 5 Howick Place, London SW1P 1WG. The Pharma Intelligence group is owned by Caerus Topco S.à r.l. and all copyright resides with the group.


This copy is for your personal, non-commercial use. Please do not redistribute without permission.

Printed By

UsernamePublicRestriction

Amoxicillin ‘ineffective’ for LRTI symptoms, study of 2,000 patients finds

Amoxicillin has little effect in the treatment of coughs and bronchitis and could even be harmful, an analysis has found.  

The antibiotic "is no more effective" at relieving the symptoms of lower respiratory tract infections (LRTI) than the "use of no medication", according to the study of more than 2,000 GP patients.

Patients across 12 European countries who were suffering from LRTI were given either amoxicillin or a placebo three times a day for seven days, in the study published in the Lancet. 

The antibiotic "is no more effective" at relieving the symptoms of lower respiratory tract infections (LRTI) than the "use of no medication".

More clinical news

Use analgesics in infants with fever 'only if distressed', Nice says

Pharmacists urged to target diabetes in south Asian communities

European Medicines agency gives green light to first meningitis B vaccine

The researchers found there was little difference in the duration of the patients' symptoms between the groups, although new or worsening symptoms were less common among the amoxicillin group.

They also found 29 per cent of patients taking amoxicillin suffered side effects including nausea, rash and diarrhoea, compared to 24 per cent in the placebo group.

"Patients given amoxicillin don't recover much quicker or have significantly fewer symptoms," said Paul Little of the University of Southampton who led the research.

"Our results show that most people get better on their own. But, given that a small number of patients will benefit from antibiotics the challenge remains to identify these individuals," he said.

The self-care forum said the study provided further evidence that most coughs and colds could be self-treated.

"Andtibiotics don't work in the treatment of coughs, colds and sore throats and evidence shows that coughs last three weeks, and sore throats a week, no matter what we do," said GP Dr Pete Smith.

As part of last month's European Antibiotics Awareness Day organised by the European Centre for Disease Prevention and Control, patients were reminded about the unnecessary overuse of antibiotics, which it was warned could encourage antibiotic resistance.


How effective do you think amoxicillin is for the treatment of coughs and bronchitis?

Comment below or email us at [email protected] You can also find C+D on Twitter, LinkedIn and Facebook

Topics

         
Pharmacy Manager
Newquay, Cornwall
£ Competitive

Apply Now
Latest News & Analysis
See All
UsernamePublicRestriction

Register

CD015887

Ask The Analyst

Please Note: You can also Click below Link for Ask the Analyst
Ask The Analyst

Thank you for submitting your question. We will respond to you within 2 business days. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel